Download e-book for kindle: Bipolar Disorders: 2nd Stanley Symposium, Freiburg, November by J. Walden, H. Grunze

By J. Walden, H. Grunze

Complement factor: Neuropsychobiology 2002, Vol. forty five, Suppl. 1

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Additional resources for Bipolar Disorders: 2nd Stanley Symposium, Freiburg, November 2000 (Neuropsychobiology)

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Case Reports Case 1 Mr. B. is a 34-year-old patient with bipolar I disorder and a rapid cycling course. His first depressive episode occurred at the age of 13, the first mania at the age of 15. Shortly after he developed a rapid cycling course with mood switches every 14 days and without any symptom-free interval. Combination treatment of lithium and carbamazepine led to a complete remission of symptoms for 15 years. Then the ultrarapid cycling reoccurred, and additionally he developed comorbid kleptomania, panic attacks, binge-eating disorder and marihuana abuse.

The graphical representation allows the overview at one glance, but on the other hand the effort needed to make the underlying data available – even if necessary – can be quite demanding. Patients frequently feel swamped with the load of documentation, even if the time needed for the prospective documentation is very short. But, although some patients suffer from the stronger awareness that results from the use of a diary, the majority is satisfied with the possibility to actively contribute to the management of their bipolar disorder.

Additionally, manic patients are still treated with typical antipsychotics in the acute phase and even as maintenance treatment, despite the high risk of tardive dyskinesia [5, 6]. A longitudinal study could also demonstrate that the long-term use of neuroleptic agents was associated with a cycle acceleration and thus a worsening of the long-term course of the illness [7]. In another double-blind study in which lithium monotherapy was compared to the combination treatment of lithium and flupentixol for 2 years, patients randomized to combination treatment suffered from more depressive episodes while the frequency of manic episodes was not significantly different [8].

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Bipolar Disorders: 2nd Stanley Symposium, Freiburg, November 2000 (Neuropsychobiology) by J. Walden, H. Grunze


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