Get Biomedical Optical Imaging Technologies: Design and PDF

By Jianhua Zhao, Haishan Zeng (auth.), Rongguang Liang (eds.)

ISBN-10: 364228390X

ISBN-13: 9783642283901

ISBN-10: 3642283918

ISBN-13: 9783642283918

This ebook presents an creation to layout of biomedical optical imaging applied sciences and their functions. the most subject matters contain: fluorescence imaging, confocal imaging, micro-endoscope, polarization imaging, hyperspectral imaging, OCT imaging, multimodal imaging and spectroscopic structures.

Each bankruptcy is written by way of the area leaders of the respective fields, and should disguise:

  • principles and barriers of optical imaging technology,
  • system layout and useful implementation for one or particular functions, together with layout guidance, process configuration, optical layout, part standards and choice, procedure optimization and layout examples,
  • recent advances and functions in biomedical researches and scientific imaging.

This e-book serves as a reference for college kids and researchers in optics and biomedical engineering.

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Extra resources for Biomedical Optical Imaging Technologies: Design and Applications

Example text

For diffuse reflectance and fluorescence spectroscopy probes, the readers can refer to the review article of Utzinger et al. [27]. Here, we are 1 Advanced Spectroscopy Technique for Biomedicine 21 focusing on real-time in vivo Raman spectroscopy system design. First, we present the designing aspects of two real-time Raman spectroscopy systems: one for in vivo skin diagnosis and the other for endoscopic in vivo lung cancer diagnosis. Then we introduce an in vivo confocal Raman spectroscopy system for skin research, followed by a summary of other types of probes for different applications.

The spectra of the mouse oral mucosa were obtained from 10 to 100 s. They found a specificity of 93% and a sensitivity of 78% for detecting low-grade dysplasia and a specificity of 100% and a sensitivity of 100% for detecting highgrade dysplasia/carcinoma in situ. Malini et al. evaluated the ability of Raman spectroscopy to differentiate normal, inflammatory, premalignant, and malignant oral lesions of biopsied tissue [69]. A set of the Raman spectra was shown in Fig. 23. Each spectrum was obtained with an integration time of 600 s.

Therefore, the 54 fibers were specially aligned for hardware binning. Following the previous work, the exact shape of the parabolic image was determined by measuring the curvature of the image of the standard slit. 10) where x was the displacement along the horizontal direction and y was the distance of the slit away from the center of the slit along the vertical direction, both in m. When such an arrangement of fibers replaced the entrance slit with orientation opposite to the image curvature, it resulted in a straight line image at the center of the CCD.

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Biomedical Optical Imaging Technologies: Design and Applications by Jianhua Zhao, Haishan Zeng (auth.), Rongguang Liang (eds.)

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